Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776412 | 1.00 | APOBEC3A (0.32) | APOBEC3AAPOBEC3GSLC6A9HDAC1HDAC8 | |
| SCHEMBL4797619 | 0.92 | KDM4E (0.34) | SLC6A9 | |
| SCHEMBL4797630 | 0.92 | KDM4E (0.34) | SLC6A9 | |
| SCHEMBL4780879 | 0.90 | CYP2E1 (0.35) | APOBEC3AAPOBEC3GSLC6A9 | |
| SCHEMBL4780874 | 0.90 | CYP2E1 (0.35) | APOBEC3AAPOBEC3GSLC6A9 | |
| SCHEMBL4781957 | 0.87 | PI4KB (0.32) | — | |
| SCHEMBL4781951 | 0.87 | PI4KB (0.32) | — | |
| SCHEMBL4776428 | 0.86 | NR1I2 (0.33) | APOBEC3AAPOBEC3GSLC6A9 | |
| SCHEMBL4776435 | 0.86 | NR1I2 (0.33) | APOBEC3AAPOBEC3GSLC6A9 | |
| SCHEMBL4138718 | 0.86 | APOBEC3A (0.33) | APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |