Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4776618 | 0.84 | KDM4E (0.41) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL4781623 | 0.78 | KDM4E (0.44) | MAPTKDM4EALDH1A1ATAD2CA12 | |
| SCHEMBL31000736 | 0.77 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL20840130 | 0.73 | KDM4E (0.42) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL24090460 | 0.72 | ATM (0.45) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL976070 | 0.72 | KDM4E (0.48) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL9721533 | 0.72 | HDAC1 (0.52) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL4779436 | 0.72 | ABL1 (0.40) | MAPTHPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL19822892 | 0.70 | CHRM4 (0.60) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5204247 | 0.69 | KDM4E (0.61) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015196-A1 | 5-,7-BIS-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES | NYCOMED GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |