Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824173 | 0.89 | FABP4 (0.54) | FABP4KDM4EMEN1KMT2ANR1H2 | |
| SCHEMBL5314054 | 0.84 | FABP4 (0.46) | FABP4BCAT2IKBKBKDM4EMEN1 | |
| SCHEMBL27599997 | 0.84 | FABP4 (0.46) | FABP4BCAT2IKBKBKDM4EMEN1 | |
| SCHEMBL6173691 | 0.83 | FABP4 (0.45) | FABP4BCAT2IKBKBKDM4EMEN1 | |
| SCHEMBL26669291 | 0.82 | FABP4 (0.45) | FABP4BCAT2IKBKBKDM4EMEN1 | |
| SCHEMBL3763563 | 0.81 | FABP4 (0.43) | FABP4BCAT2IKBKBKDM4EMEN1 | |
| SCHEMBL530568 | 0.81 | FABP4 (0.58) | FABP4BCAT2IKBKBNR1H2NR1H3 | |
| SCHEMBL30339795 | 0.81 | FABP4 (0.58) | FABP4BCAT2IKBKBNR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL28812647 | 0.79 | FABP4 (0.57) | FABP4BCAT2IKBKBNR1H2NR1H3 | |
| SCHEMBL10430504 | 0.79 | MAP2 (0.47) | BCAT2IKBKBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891064-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | Laboratorios Almirall, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006133802-A1 | N-AMIDE DERIVATIVES OF 8-AZABICYCLO[3.2.1]OCT-3-YL AS CCR1 ANTAGONISTS | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |