Tetramethylammonium Ion

Tetramethylammonium Ion

SCHEMBL4776563

COC(=O)CC(=O)OC.C[N+](C)(C)C

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.58
GAA P10253 2/20 0.58
SI P14410 2/20 0.58
MGAM2 Q2M2H8 2/20 0.58
TSHR P16473 4/20 0.56
HSD17B10 Q99714 2/20 0.50
KMT2A Q03164 2/20 0.40
TET2 Q6N021 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.39
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
CA12 O43570 1/20 0.39
CA14 Q9ULX7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
RECQL P46063 1/20 0.39
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL53913 0.89
SCHEMBL3441102 0.89 MGAM (0.69) MGAMGAASIMGAM2TSHR
SCHEMBL11587161 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL4776595 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
Lithium SCHEMBL11306430 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
Hydrochloric Acid SCHEMBL5097295 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL708003 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL9461843 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
SCHEMBL29911291 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR
Bromide SCHEMBL29190335 0.86 MGAM (0.65) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1878493-B1 Method of making a polyisocyanurate/polyurethane foam using carbocation compounds as trimerization catalysts AIR PROD & CHEM (US) 2013-08-21 EP claimed
US-8445555-B2 Stabilized carbanions as trimerization catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-21 US claimed
US-20080015274-A1 Stabilized carbanions as trimerization catalysts EVONIK OPERATIONS GMBH (DE) 2008-01-17 US claimed
EP-1878493-A1 Stabilized carbanions as trimerization catalysts Air Products and Chemicals, Inc. (US) 2008-01-16 EP claimed
EP-1878493-B1 Method of making a polyisocyanurate/polyurethane foam using carbocation compounds as trimerization catalysts AIR PROD & CHEM (US) 2013-08-21 EP disclosed
US-8445555-B2 Stabilized carbanions as trimerization catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-21 US disclosed
US-20080015274-A1 Stabilized carbanions as trimerization catalysts EVONIK OPERATIONS GMBH (DE) 2008-01-17 US disclosed
EP-1878493-A1 Stabilized carbanions as trimerization catalysts Air Products and Chemicals, Inc. (US) 2008-01-16 EP disclosed