Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | SI | P14410 | 2/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL53913 | 0.96 | — | — | |
| SCHEMBL3441102 | 0.96 | MGAM (0.69) | MGAMGAASIMGAM2TSHR | |
| Lithium SCHEMBL11306430 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| Bromide SCHEMBL29190335 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL29911291 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11587161 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| Hydrochloric Acid SCHEMBL5097295 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL4776595 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9461843 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27296203 | 0.92 | MGAM (0.65) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010633-B | Synthesis method and device of ring-closing compound | 宁夏汉润生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115043764-B | Synthesis method of clethodim intermediate | 宁夏汉润生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115043764-A | Synthetic method of clethodim intermediate | 宁夏汉润生物科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-115010633-A | Synthetic method and device of ring closing object | 宁夏汉润生物科技有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-111362850-B | Improved process for carrying out cyclization and continuous feed apparatus therefor | 内蒙古兰格生物科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-111362850-A | Improved process for carrying out cyclization and continuous feed apparatus therefor | 内蒙古兰格生物科技有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-108530277-A | A kind of preparation method of m-hydroxy acetophenone | 江西永通科技股份有限公司 | 2018-09-14 | — | — | CN | claimed |
| US-20170008863-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | CHONG, HYUN-SOON, PHD | 2017-01-12 | — | — | US | claimed |
| CN-104892472-B | Double chiral sulfoxides-alkene part compounds and its preparation method and application | 同济大学 | 2016-10-19 | — | — | CN | claimed |
| CN-105051013-A | Laquinimod sodium crystals and improved process for their manufacture | TEVA PHARMA | 2015-11-11 | — | — | CN | claimed |
| CN-104892472-A | Bis-chiral sulfoxide-alkene ligand compound, and preparation method and application thereof | UNIV TONGJI | 2015-09-09 | — | — | CN | claimed |
| US-20130310555-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2013-11-21 | — | — | US | claimed |
| EP-1878493-B1 | Method of making a polyisocyanurate/polyurethane foam using carbocation compounds as trimerization catalysts | AIR PROD & CHEM (US) | 2013-08-21 | — | — | EP | claimed |
| US-20080015274-A1 | Stabilized carbanions as trimerization catalysts | EVONIK OPERATIONS GMBH (DE) | 2008-01-17 | — | — | US | claimed |
| EP-1878493-A1 | Stabilized carbanions as trimerization catalysts | Air Products and Chemicals, Inc. (US) | 2008-01-16 | — | — | EP | claimed |
| EP-0051233-B1 | PROCESS FOR THE PREPARATION OF 13-OXABICYCLO-(10.3.0)PENTADECANE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-08-08 | — | — | EP | claimed |
| US-4360468-A | Preparation of 13-oxabicyclo[10.3.0]pentadecane | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-11-23 | — | — | US | claimed |
| EP-3599854-B1 | PYRROLIDINONES AND A PROCESS TO PREPARE THEM | FMC CORP (US) | 2026-05-06 | — | — | EP | disclosed |
| US-4360468-A | Preparation of 13-oxabicyclo[10.3.0]pentadecane | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-11-23 | — | — | US | disclosed |
| US-4001279-A | CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008863-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | AZI2, ABL1, DHPS | MGAM 2758/4885GAA 398/4885SI 878/4885 |
| US-20130310555-A1 | SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS | AZI2, ABL1, DHPS | MGAM 2758/4885GAA 398/4885SI 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.