Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776723 | 0.95 | LMNA (0.58) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4776712 | 0.95 | LMNA (0.58) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28407614 | 0.94 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8406469 | 0.88 | LMNA (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL16269716 | 0.87 | TTR (0.40) | CA12CA1CA2CA9POLB | |
| SCHEMBL4778070 | 0.86 | CA12 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8057064 | 0.86 | CA12 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28965738 | 0.86 | TTR (0.40) | CA12CA1CA2CA9POLB | |
| SCHEMBL28525196 | 0.84 | MAPT (0.41) | CA12CA1CA2CA9HTT | |
| SCHEMBL7738661 | 0.83 | CA12 (0.51) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398367-B1 | Cleaning compositions containing multiply-substituted protease variants | GENENCOR INT (US) | 2008-12-10 | — | — | EP | disclosed |
| EP-0723579-B1 | PROTEASE-CONTAINING CLEANING COMPOSITIONS | PROCTER & GAMBLE (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1398367-A1 | Cleaning compositions containing multiply-substituted protease variants | THE PROCTER & GAMBLE COMPANY (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-0929577-B1 | STABILIZED PROTEINACEOUS PROTEASE INHIBITORS AND VARIANTS THEREOF | PROCTER & GAMBLE (US) | 2003-06-04 | — | — | EP | disclosed |
| US-5773399-A | STORAGE STABILITY FOR DETERGENTS USING SURFACTANTS, SILICATE, SULFATE SALTS WITH PERCARBONATE BLEACHING AGENTS | THE PROCTER & GAMBLE COMAPNY (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1996028558-A9 | THERMITASE VARIANTS HAVING DECREASED ADSORPTION AND INCREASED HYDROLYSIS | — | 1997-01-16 | — | — | WO | disclosed |
| EP-0708819-A1 | A DETERGENT COMPOSITION COMPRISING TWO CELLULASE COMPONENTS | NOVO NORDISK A/S (DK) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002675-A1 | A DETERGENT COMPOSITION COMPRISING TWO CELLULASE COMPONENTS | NOVO NORDISK A/S (DK) | 1995-01-26 | — | — | WO | disclosed |