Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946285 | 1.00 | HTR6 (0.63) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL946440 | 1.00 | HTR6 (0.63) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL945805 | 0.89 | HTR6 (0.62) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL4775446 | 0.89 | HTR6 (0.62) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL945926 | 0.89 | HTR6 (0.62) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL4779902 | 0.88 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947246 | 0.88 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947244 | 0.88 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL946272 | 0.87 | HTR6 (0.69) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL4772641 | 0.87 | HTR6 (0.69) | HTR6CYP3A4CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | claimed |
| EP-1581492-A1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Suven Life Sciences Limited (IN) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004048330-A1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |