Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776986 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL1794388 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL1795653 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL1797151 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL1795410 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL1797148 | 0.91 | CHRNB4 (0.50) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL13403267 | 0.89 | CHRNB4 (0.49) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL4782463 | 0.87 | OPRM1 (0.44) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL3538856 | 0.86 | CHRNB4 (0.55) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL5187982 | 0.86 | CHRNB4 (0.55) | CHRNB4CHRNA3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |