Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 5/20 | 0.49 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.49 |
| ▸ | INPP5B | P32019 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053131 | 1.00 | INPPL1 (0.49) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL845399 | 0.82 | GPR35 (0.51) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL845400 | 0.82 | GPR35 (0.51) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL2438828 | 0.81 | INPPL1 (0.49) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL12487138 | 0.81 | INPPL1 (0.49) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL2438837 | 0.81 | INPPL1 (0.49) | INPPL1INPP5AINPP5BCA1CA2 | |
| SCHEMBL104227 | 0.78 | TDP1 (0.53) | ALDH1A1KDM4EHPGDTP53TDP1 | |
| SCHEMBL28665448 | 0.77 | INPPL1 (0.55) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL2851716 | 0.75 | INPPL1 (0.59) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL569537 | 0.75 | INPPL1 (0.57) | INPPL1INPP5AINPP5BSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2715356-B1 | TSH IMMUNOASSAYS EMPLOYING SCAVENGING REAGENTS FOR CROSS-REACTING ENDOCRINE GLYCOPROTEIN HORMONE ANALOGUES | ABBOTT POINT OF CARE INC (US) | 2017-04-26 | — | — | EP | disclosed |
| US-9575077-B2 | TSH antibodies for point-of-care immunoassay formats | ABBOTT POINT OF CARE INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9575076-B2 | TSH immunoassays and processes for performing TSH immunoassays in the presence of endogenous contaminants in restricted wash formats | ABBOTT POINT OF CARE INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160109465-A1 | TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS | ABBOTT POINT OF CARE INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-20160109466-A1 | TSH ANTIBODIES FOR POINT-OF-CARE IMMUNOASSAY FORMATS | ABBOTT POINT OF CARE INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-9199234-B2 | TSH antibodies for point-of-care immunoassay formats | ABBOTT POINT OF CARE INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9201078-B2 | TSH immunoassays and processes for performing TSH immunoassays in the presence of endogenous contaminants in restricted wash formats | ABBOTT POINT OF CARE INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9068994-B2 | TSH immunoassays employing scavenging reagents for cross-reacting endocrine glycoprotein hormone analogues | ABBOTT POINT OF CARE INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-8703445-B2 | Molecular diagnostics amplification system and methods | ABBOTT POINT OF CARE INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-20140072989-A1 | TSH IMMUNOASSAYS EMPLOYING SCAVENGING REAGENTS FOR CROSS-REACTING ENDOCRINE GLYCOPROTEIN HORMONE ANALOGUES | ABBOTT POINT OF CARE INC. (US) | 2014-03-13 | — | — | US | disclosed |
| WO-2012166200-A1 | TSH IMMUNOASSAYS EMPLOYING SCAVENGING REAGENTS FOR CROSS-REACTING ENDOCRINE GLYCOPROTEIN HORMONE ANALOGUES | ABBOTT POINT OF CARE INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012166199-A1 | TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS | ABBOTT POINT OF CARE INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012166198-A1 | TSH ANTIBODIES FOR POINT-OF-CARE IMMUNOASSAY FORMATS | ABBOTT POINT OF CARE INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| US-20120301896-A1 | TSH ANTIBODIES FOR POINT-OF-CARE IMMUNOASSAY FORMATS | ABBOTT POINT OF CARE INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120301906-A1 | TSH IMMUNOASSAYS EMPLOYING SCAVENGING REAGENTS FOR CROSS-REACTING ENDOCRINE GLYCOPROTEIN HORMONE ANALOGUES | ABBOTT POINT OF CARE INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120301905-A1 | TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS | ABBOTT POINT OF CARE INC. (US) | 2012-11-29 | — | — | US | disclosed |
| EP-1966366-A2 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078850-A9 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I STAT CORP (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007078850-A2 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070154922-A1 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |