Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 15/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780247 | 0.82 | BCHE (0.61) | NOX1BCHEACHEHTR1AADRB3 | |
| SCHEMBL4779900 | 0.79 | BCHE (0.70) | NOX1BCHEMEN1KMT2AACHE | |
| SCHEMBL5805862 | 0.79 | NOX1 (0.56) | NOX1BCHEMEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL5804919 | 0.78 | BCHE (0.68) | NOX1BCHEMEN1KMT2AACHE | |
| SCHEMBL15775866 | 0.71 | MEN1 (0.55) | NOX1BCHEMEN1KMT2AACHE | |
| SCHEMBL14746015 | 0.70 | BCHE (0.66) | BCHEACHEADRB3HTR2ASLC6A3 | |
| SCHEMBL15775178 | 0.68 | MEN1 (0.44) | NOX1BCHEMEN1KMT2AHTR1A | |
| SCHEMBL27597035 | 0.68 | BCHE (0.51) | NOX1BCHEMEN1KMT2AACHE | |
| SCHEMBL30300504 | 0.67 | BCHE (0.73) | NOX1BCHEACHEHTR1AADRB3 | |
| SCHEMBL4446747 | 0.67 | BCHE (0.73) | NOX1BCHEACHEHTR1AADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | claimed |
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | disclosed |