Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778811 | 0.82 | LMNA (0.51) | MEN1KMT2ALMNAPTGS1PTGS2 | |
| SCHEMBL15775866 | 0.79 | MEN1 (0.55) | MEN1KMT2ALMNAPTGS1PTGS2 | |
| SCHEMBL9231844 | 0.75 | PIM1 (0.48) | MEN1KMT2ALMNAPTGS1PTGS2 | |
| SCHEMBL18640386 | 0.74 | PIM1 (0.43) | MEN1KMT2ALMNAPTGS1PTGS2 | |
| Ammonia Solution, Strong SCHEMBL22186858 | 0.73 | PTGS1 (0.49) | MEN1KMT2ALMNAPTGS1PTGS2 | |
| SCHEMBL7067788 | 0.72 | CYP2D6 (0.72) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL5805862 | 0.70 | NOX1 (0.56) | MEN1KMT2ANOX1BCHESLC6A3 | |
| SCHEMBL4779900 | 0.70 | BCHE (0.70) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL17079876 | 0.70 | KDM1A (0.74) | MEN1KMT2ALMNAPTGS1MAPT | |
| SCHEMBL1458306 | 0.69 | CYP2D6 (0.74) | MEN1KMT2ALMNAPTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | claimed |
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |