SCHEMBL47771

SCHEMBL47771

CN=C1C=CC(=Nc2ccc(Nc3ccc(N(C)c4ccc(C)cc4)cc3)cc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
GAA P10253 1/20 0.35
G6PD P11413 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HTT P42858 1/20 0.35
BLM P54132 1/20 0.35
ENPP2 Q13822 1/20 0.34
ALDH1A1 P00352 4/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
GFER P55789 1/20 0.31
MCL1 Q07820 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRIN2D O15399 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13899818 0.89 HPGD (0.44) HPGDMEN1KMT2AGAAG6PD
SCHEMBL13707594 0.89 HPGD (0.44) HPGDMEN1KMT2AGAAG6PD
SCHEMBL47774 0.89 HPGD (0.44) HPGDMEN1KMT2AGAAG6PD
SCHEMBL16229251 0.89 HPGD (0.44) HPGDMEN1KMT2AGAAG6PD
SCHEMBL14594146 0.83 HPGD (0.50) HPGDMEN1KMT2AGAAG6PD
SCHEMBL12309398 0.79 MAPT (0.39) HPGDMEN1KMT2AL3MBTL1HTT
SCHEMBL821944 0.79 MAPT (0.39) HPGDMEN1KMT2AL3MBTL1HTT
SCHEMBL677862 0.79 MAPT (0.39) HPGDMEN1KMT2AL3MBTL1HTT
SCHEMBL21091591 0.77 ALDH1A1 (0.48) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL13707595 0.77 HPGD (0.44) HPGDMEN1KMT2AGAAG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129025-B2 Fluorotelomer grafted polyaniline containing intermediate transfer members XEROX CORPORATION (US) 2012-03-06 US disclosed
US-20100247919-A1 FLUOROTELOMER GRAFTED POLYANILINE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2010-09-30 US disclosed