Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 4/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11052815 | 0.98 | TSHR (0.55) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| Ammonia Solution, Strong SCHEMBL27869906 | 0.98 | TSHR (0.55) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| SCHEMBL28102712 | 0.98 | TSHR (0.55) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| Dimethylamine SCHEMBL27508680 | 0.95 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| SCHEMBL39857 | 0.86 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4EHSD17B10APEX1 | |
| SCHEMBL28160277 | 0.85 | TSHR (0.53) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| SCHEMBL5011915 | 0.85 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| SCHEMBL698873 | 0.85 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EHSD17B10NOTUM | |
| Hydrochloric Acid SCHEMBL699717 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4EHSD17B10APEX1 | |
| SCHEMBL3327287 | 0.83 | NR4A2 (0.51) | TSHRALDH1A1KDM4EHSD17B10NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551633-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2021-03-31 | — | — | EP | claimed |
| CN-110088108-A | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | 利奥制药有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-106146288-A | A kind of post processing separation method of aromatic hydroxy carboxy acid's intermediate 3,6 dichloro 2 methoxybenzoic acid | 陈云华 | 2016-11-23 | — | — | CN | claimed |
| CN-101160049-B | Spiroketal-substituted cyclic ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-11 | — | — | CN | claimed |
| CN-103819327-B | The synthetic method of the chloro-O-Anisic Acid of a kind of 3,6-bis- | ZHEJIANG SHENGHUA BIOK BIOLOGY CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-102740697-B | Composition pesticide | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-13 | — | — | CN | claimed |
| CN-105461549-A | Synthesis technology of glibenclamide intermediate 5-chloro-2-methoxyben zoic acid | TIANJIN PHARMACEUTICAL GROUP GENCOM PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105294419-A | Synthesis methods of 3, 6-dichloro-2-methoxybenzoic acid and its intermediate | JIANGSU LIANHE CHEMICAL TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105237422-A | Synthetic method of 4-amino-5-chloro-2-methoxyl benzoic acid | UNIV NANJING SCIENCE & TECH | 2016-01-13 | — | — | CN | claimed |
| CN-105237445-A | Synthetic process of 4-[2-(5-chloro-2-methoxy benzamide)ethyl]benzsulfamide | DALIAN JOIN KING BIOCHEM TECH CO LTD | 2016-01-13 | — | — | CN | claimed |
| CN-1173280-A | Synergistic composition and process for selective weed control | CIBA GEIGY AG (CH) | 1998-02-18 | — | — | CN | claimed |
| CN-1137346-A | Synergistic weedicide composite | SICHUAN PROV NATURAL RESOURCES (CN) | 1996-12-11 | — | — | CN | claimed |
| CN-1089431-A | Method for enhancing herbicidal activity, herbicidal composition with enhanced activity and composition with enhanced activity | ISHIHARA SANGYO KAISHA (JP) | 1994-07-20 | — | — | CN | claimed |
| CN-1024488-C | Benzhydryl compounds as henbicide antidotes | MONSANTO CO (US) | 1994-05-18 | — | — | CN | claimed |
| CN-1078350-A | Synergistic composition and method for selective weed control | CIBA GEIGY AG (CH) | 1993-11-17 | — | — | CN | claimed |
| CN-1075846-A | Chemically stabilized herbicidal oil-based suspensions | ISHIHARA SANGYO KAISHA (JP) | 1993-09-08 | — | — | CN | claimed |
| US-5227514-A | Water soluble analgesic | LONZA LTD. (CH) | 1993-07-13 | — | — | US | claimed |
| CN-1064274-A | The pyridinesulfonamide compound or its salt, their preparation method and the weedicide that contains above-claimed cpd that replace | ISHIHARA SANGYO KAISHA (JP) | 1992-09-09 | — | — | CN | claimed |
| CN-1039949-A | The protection of benzoic acid derivative class weed killer herbicide | MONSANTO CO (US) | 1990-02-28 | — | — | CN | claimed |
| CN-1031174-A | Herbicidal combinations | ISHIHARA SANGYO KAISHA (JP) | 1989-02-22 | — | — | CN | claimed |