⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070145 | 1.00 | — | — | |
| SCHEMBL9637160 | 1.00 | — | — | |
| SCHEMBL1903763 | 1.00 | — | — | |
| SCHEMBL7673861 | 1.00 | — | — | |
| SCHEMBL386177 | 1.00 | — | — | |
| SCHEMBL3804023 | 0.89 | LMNA (0.42) | — | |
| SCHEMBL18423851 | 0.86 | SIRT2 (0.37) | — | |
| SCHEMBL5698597 | 0.84 | SIRT2 (0.36) | — | |
| SCHEMBL21353932 | 0.83 | SIRT2 (0.35) | — | |
| SCHEMBL9701164 | 0.82 | CPT2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516014-B1 | POROUS GELATIN MATERIAL, GELATIN STRUCTURES, METHODS FOR PREPARATION OF THE SAME AND USES THEREOF | CELLTRIX AB (SE) | 2016-11-02 | — | — | EP | claimed |
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | SEAPORT THERAPEUTICS, INC. | 2024-06-27 | — | — | US | disclosed |
| US-11975073-B2 | Lipid prodrugs of neurosteroids | PURETECH LYT, INC. (US) | 2024-05-07 | — | — | US | disclosed |
| CN-117865872-A | Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11938137-B2 | Lipid prodrugs of mycophenolic acid and uses thereof | PURETECH LYT, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| WO-2024028316-A1 | 1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF MUTANT EGFR FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-08 | — | — | WO | disclosed |
| US-11883497-B2 | Lymphatic system-directing lipid prodrugs | PURETECH LYT, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| EP-4306524-A2 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | PureTech LYT, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-112375078-B | Tetrahydro-pyrido [3,4-b ] indole estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-0159565-A1 | Substituted 2,3,3alpha,6-tetrahydro-6-oxabenzofuran derivatives useful as paf antagonists | MERCK & CO. INC. (US) | 1985-10-30 | — | — | EP | disclosed |
| EP-0154887-A1 | New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |
| EP-0151687-A1 | Process for the isolation of 5-Allyl-2-(3,4-dimethoxyphenyl)-3a-methoxy-3-methyl-2,3,3a,6-tetrahydro-6-oxobenzofuran and pharmaceutical composition for treating inflammatory conditions | MERCK & CO. INC. (US) | 1985-08-21 | — | — | EP | disclosed |
| EP-0144804-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0142801-A2 | Indene derivatives useful as paf-antagonists | MERCK & CO. INC. (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0124081-A2 | New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them | MERCK & CO. INC. (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0109036-A1 | Anti-inflammatory/analgesic combination of alpha-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID) | MERCK & CO. INC. (US) | 1984-05-23 | — | — | EP | disclosed |
| EP-0083779-A1 | Hyperuretic agents | Beyer, Karl H., Jr. (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0081823-A1 | Composition for reducing menstrual pain | WHITBY RESEARCH, Inc. (US) | 1983-06-22 | — | — | EP | disclosed |
| US-4135879-A | PHOSPHORIC ACID ESTERS OF POLYOXYETHYLATED ALKANOLS AND/OR SALTS THEREOF | CHEMISCHE FABRIK KREUSSLER & CO., GMBH (DE) | 1979-01-23 | — | — | US | disclosed |