Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778583 | 0.96 | NAAA (0.51) | NAAASMN1; SMN2SLC18A3CYP19A1EPHX2 | |
| SCHEMBL4778563 | 0.88 | NAAA (0.42) | NAAASMN1; SMN2SLC18A3CYP19A1LMNA | |
| SCHEMBL11006772 | 0.83 | NAAA (0.67) | NAAASMN1; SMN2TSHRCYP19A1LMNA | |
| SCHEMBL28446549 | 0.82 | NAAA (0.62) | NAAASMN1; SMN2SLC18A3PRKCA | |
| SCHEMBL28446547 | 0.82 | NAAA (0.62) | NAAASMN1; SMN2SLC18A3PRKCA | |
| SCHEMBL3189677 | 0.81 | NAAA (0.71) | NAAALMNAPRKCA | |
| SCHEMBL19150294 | 0.81 | CYP19A1 (0.53) | NAAASMN1; SMN2TSHRSLC18A3CYP19A1 | |
| SCHEMBL3189683 | 0.81 | NAAA (0.71) | NAAALMNAPRKCA | |
| SCHEMBL3179079 | 0.79 | NAAA (0.74) | NAAALMNAPRKCA | |
| SCHEMBL3179072 | 0.79 | NAAA (0.74) | NAAALMNAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | claimed |
| CN-106309421-B | Pharmaceutical composition and cosmetic composition | 沃凯索法株式会社 | 2020-08-25 | — | — | CN | disclosed |
| US-8420853-B2 | Derivatives of cyclic compound and the use thereof | Wonkisopharm Co., Ltd (KR) | 2013-04-16 | — | — | US | disclosed |
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | disclosed |