Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922760 | 0.78 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL707943 | 0.75 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL6369193 | 0.74 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4303218 | 0.74 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL706949 | 0.74 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL4303215 | 0.70 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL4304138 | 0.69 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL4298845 | 0.69 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL3861862 | 0.68 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL2796210 | 0.68 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |