SCHEMBL4777446

SCHEMBL4777446

C=CC(OC(=O)C(=C)C)O[Si](OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2203797 0.80 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL1155550 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL10871051 0.78 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL3356298 0.77 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL9559905 0.77 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL7644159 0.76 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL10871045 0.76 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL27771712 0.74 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL6060742 0.74 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL11576486 0.73 ALDH1A1 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1365915-A4 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME SURFACE LOGIX INC (US) 2008-06-25 EP claimed
US-6770721-B1 PATTERNING TRANSFER ELEMENT COMPRISING CROSSLINKED HYDROXYETHYL METHACRYLATE COPOLYMER HAVING ELEVATED AND RECESSED PORTIONS; HIGH THROUGHPUT DRUG SCREENING SURFACE LOGIX, INC. 2004-08-03 US claimed
EP-1365915-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME Surface Logix, Inc. (US) 2003-12-03 EP claimed
WO-2002036342-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME SURFACE LOGIX, INC. (US) 2002-05-10 WO claimed
EP-1365915-A4 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME SURFACE LOGIX INC (US) 2008-06-25 EP disclosed
US-20040247912-A1 Polymer gel contact masks and methods and molds for making same KIM ENOCH (US) 2004-12-09 US disclosed
US-6770721-B1 PATTERNING TRANSFER ELEMENT COMPRISING CROSSLINKED HYDROXYETHYL METHACRYLATE COPOLYMER HAVING ELEVATED AND RECESSED PORTIONS; HIGH THROUGHPUT DRUG SCREENING SURFACE LOGIX, INC. 2004-08-03 US disclosed
EP-1365915-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME Surface Logix, Inc. (US) 2003-12-03 EP disclosed
WO-2002036342-A1 POLYMER GEL CONTACT MASKS AND METHODS AND MOLDS FOR MAKING SAME SURFACE LOGIX, INC. (US) 2002-05-10 WO disclosed