Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769594 | 0.90 | GAA (0.48) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4771213 | 0.88 | GAA (0.71) | GAAALDH1A1MAPTLMNAHPGD | |
| SCHEMBL14497659 | 0.88 | GAA (0.59) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4774743 | 0.85 | ALDH1A1 (0.60) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4768069 | 0.85 | GAA (0.64) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4776615 | 0.83 | GAA (0.68) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4777288 | 0.82 | GAA (0.61) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4772417 | 0.81 | GAA (0.66) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4777696 | 0.81 | GAA (0.66) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL4777345 | 0.80 | GAA (0.55) | GAAALDH1A1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |