Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | CELA1 | Q9UNI1 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092739 | 0.81 | MEN1 (0.34) | HSD17B10CES2CES1CA1CA2 | |
| SCHEMBL1994881 | 0.80 | CA1 (0.43) | CYP4F2CYP4A11PREPCELA1KDR | |
| SCHEMBL22701893 | 0.78 | CYP4F2 (0.37) | POLBNLRP3CYP4F2CYP4A11PREP | |
| SCHEMBL28540877 | 0.78 | CYP4F2 (0.40) | POLBNLRP3CYP4F2CYP4A11PREP | |
| SCHEMBL7182462 | 0.76 | KDM4E (0.45) | POLBCYP4F2CYP4A11PREPCELA1 | |
| SCHEMBL570928 | 0.75 | PREP (0.39) | POLBCYP4F2CYP4A11PREPCELA1 | |
| SCHEMBL7879433 | 0.74 | CYP4F2 (0.37) | POLBNLRP3CYP4F2CYP4A11PREP | |
| SCHEMBL7711877 | 0.74 | CYP4F2 (0.44) | POLBCYP4F2CYP4A11TOP1BACE1 | |
| SCHEMBL22118212 | 0.73 | — | — | |
| SCHEMBL12342059 | 0.73 | KDM4E (0.42) | POLBCYP4F2CYP4A11PREPCELA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108633-A | Preparation method of L-glufosinate intermediate (S) -2- (((benzyloxy) carbonyl) amino) but-3-enoic acid methyl ester | 浙江工业大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118084706-A | Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound | 河北科技大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118026934-A | N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof | 安徽理工大学 | 2024-05-14 | — | — | CN | claimed |
| CN-117843600-A | Fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof | 浙江理工大学 | 2024-04-09 | — | — | CN | claimed |
| CN-114539302-B | P-type doped material based on triarylboron-nitrogen skeleton, and preparation method and application thereof | 广东粤港澳大湾区黄埔材料研究院 | 2024-02-02 | — | — | CN | claimed |
| CN-117486968-A | Preparation method of snake venom peptide | 深圳创元生物医药科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117304135-A | Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative | 衡阳师范学院 | 2023-12-29 | — | — | CN | claimed |
| CN-117164545-A | Reversible fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof | 浙江理工大学 | 2023-12-05 | — | — | CN | claimed |
| CN-117126178-A | Bisphenol thiazide compound and synthesis method thereof | 湘潭大学 | 2023-11-28 | — | — | CN | claimed |
| CN-113461469-A | Thioether aromatic heterocyclic compound and preparation method and application thereof | 广东工业大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113416186-A | Berberine hydrochloride dimer and preparation method and application thereof | 北京大学深圳医院 | 2021-09-21 | — | — | CN | claimed |
| CN-113149879-A | Preparation method of 4-seleno-naphthyl ester or 4-seleno-naphthyl amide | 温州医科大学 | 2021-07-23 | — | — | CN | claimed |
| CN-112979545-A | Preparation method of 5-selenoquinoline amide or 5-selenoquinoline ester | 温州医科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-109293692-B | Gem-difluoroalkyl borate compounds and preparation method and application thereof | 中山大学 | 2021-05-11 | — | — | CN | claimed |
| CN-110483460-B | Preparation method of 3-seleno-coumarin compound | 温州医科大学 | 2021-04-20 | — | — | CN | claimed |
| CN-110698322-B | Synthesis method of coastal twinborn anthane diterpene Stemarin | 浙江大学 | 2021-01-26 | — | — | CN | claimed |
| CN-110698322-A | Synthesis method of coastal twinborn anthane diterpene Stemarin | 浙江大学 | 2020-01-17 | — | — | CN | claimed |
| EP-0127235-B1 | PARTIALLY RETRO-INVERTED DECAPEPTIDE AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS | ENI-Ente Nazionale Idrocarburi (IT) | 1988-10-19 | — | — | EP | claimed |
| EP-0127234-B1 | A RETRO-INVERSO ANALOGUE OF THE (5-14) DECAPEPTIDE OF EQUINE ANGIOTENSINOGEN, AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS | ENI-Ente Nazionale Idrocarburi (IT) | 1987-09-23 | — | — | EP | claimed |