Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701893 | 0.85 | CYP4F2 (0.37) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL1994881 | 0.80 | CA1 (0.43) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL24445861 | 0.79 | PREP (0.41) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL22709346 | 0.76 | PREP (0.32) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL24436821 | 0.76 | PREP (0.41) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL24436807 | 0.76 | KDM4E (0.41) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL4777765 | 0.74 | POLB (0.38) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL25222005 | 0.74 | CYP3A4 (0.33) | MAPTCYP3A4 | |
| SCHEMBL5438858 | 0.74 | CYP4F2 (0.47) | CYP4F2CYP4A11TOP1BACE1HTT | |
| SCHEMBL29289982 | 0.73 | HTT (0.42) | CYP4F2CYP4A11TOP1BACE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333436-B1 | Styrene derivatives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |