Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4780345 | 0.94 | TRPV1 (0.56) | TRPV1CYP3A4CYP2D6 | |
| Trifluoromethanesulfonic Acid SCHEMBL4779483 | 0.92 | TRPV1 (0.51) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4781057 | 0.91 | TRPV1 (0.55) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4780302 | 0.85 | TRPV1 (0.52) | TRPV1CYP3A4 | |
| SCHEMBL4773951 | 0.82 | TRPV1 (0.56) | TRPV1CYP3A4 | |
| SCHEMBL4776314 | 0.79 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4779514 | 0.79 | KDM4E (0.53) | TRPV1CYP3A4 | |
| SCHEMBL4458303 | 0.77 | TRPV1 (0.61) | TRPV1CYP3A4 | |
| SCHEMBL4778197 | 0.77 | KDM4E (0.53) | TRPV1CYP3A4 | |
| SCHEMBL4779260 | 0.77 | TRPV1 (0.52) | TRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |