Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4780345 | 0.82 | TRPV1 (0.56) | TRPV1CYP3A4 | |
| SCHEMBL4780302 | 0.82 | TRPV1 (0.52) | KDM4EALDH1A1MAPTTRPV1CYP3A4 | |
| SCHEMBL4781057 | 0.81 | TRPV1 (0.55) | TRPV1CYP3A4 | |
| SCHEMBL4778197 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL4776314 | 0.81 | TRPV1 (0.56) | KMT2ATRPV1MEN1 | |
| SCHEMBL4774396 | 0.81 | TRPV1 (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2EPHX2 | |
| SCHEMBL4778207 | 0.81 | TRPV1 (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2EPHX2 | |
| SCHEMBL4779427 | 0.79 | EPHX2 (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2EPHX2 | |
| Trifluoroacetic Acid SCHEMBL4777995 | 0.79 | TRPV1 (0.52) | TRPV1CYP3A4 | |
| SCHEMBL4773951 | 0.79 | TRPV1 (0.56) | ALDH1A1MAPTKMT2ATRPV1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |