⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518261 | 0.90 | — | — | |
| SCHEMBL26869 | 0.89 | TK2 (0.33) | — | |
| SCHEMBL6441180 | 0.85 | P2RY6 (0.33) | — | |
| SCHEMBL4772315 | 0.85 | — | — | |
| SCHEMBL1096446 | 0.84 | — | — | |
| SCHEMBL5861676 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL2768845 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL5557385 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL7067321 | 0.83 | TK2 (0.34) | — | |
| SCHEMBL1099028 | 0.83 | TK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335765-B2 | Nucleoside and oligonucleotide analogues | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20020147332-A1 | Novel nucleoside and oligonucleotide analogues | SANKYO COMPANY, LIMITED (JP) | 2002-10-10 | — | — | US | disclosed |