Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.58 |
| ▸ | PREP | P48147 | 9/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896266 | 1.00 | DPP4 (0.67) | DPP4DPP7DPP8PREPDPP9 | |
| SCHEMBL4894739 | 0.84 | DPP4 (0.67) | DPP4DPP7DPP8PREPDPP9 | |
| SCHEMBL4894743 | 0.84 | DPP4 (0.67) | DPP4DPP7DPP8PREPDPP9 | |
| Hydrochloric Acid SCHEMBL5206597 | 0.79 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| SCHEMBL8267018 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6172699 | 0.78 | DPP4 (0.95) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5204236 | 0.78 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| SCHEMBL4900437 | 0.78 | DPP4 (0.67) | DPP4DPP7DPP8PREPDPP9 | |
| SCHEMBL4894309 | 0.76 | DPP4 (0.66) | DPP4DPP7DPP8PREPDPP9 | |
| SCHEMBL4899278 | 0.76 | DPP4 (0.70) | DPP4DPP7DPP8PREPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931633-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007029086-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |