SCHEMBL4894739

SCHEMBL4894739

N#CC1CC(F)CN1C(=O)CNC1C2CN(C(=O)O)CC21

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.67
DPP8 Q6V1X1 13/20 0.65
DPP7 Q9UHL4 12/20 0.65
PREP P48147 8/20 0.65
DPP9 Q86TI2 11/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894743 1.00 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9
SCHEMBL4896266 0.84 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9
SCHEMBL4778046 0.84 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9
SCHEMBL4900437 0.83 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9
SCHEMBL4897021 0.82 DPP4 (0.81) DPP4DPP8DPP7PREPDPP9
SCHEMBL4894309 0.82 DPP4 (0.66) DPP4DPP8DPP7PREPDPP9
SCHEMBL4899278 0.82 DPP4 (0.70) DPP4DPP8DPP7PREPDPP9
SCHEMBL4896855 0.81 DPP4 (0.65) DPP4DPP8DPP7PREPDPP9
SCHEMBL4635221 0.81 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9
SCHEMBL4889000 0.81 DPP4 (0.67) DPP4DPP8DPP7PREPDPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080300251-A1 Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors RANBAXY LABORATORIES LIMITED (IN) 2008-12-04 US claimed
US-20080300251-A1 Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors RANBAXY LABORATORIES LIMITED (IN) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300251-A1 Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors DPP4, DPP3, DPP8 DPP4 1/4885DPP8 3/4885DPP7 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.