Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772348 | 0.89 | PDE10A (0.32) | PDE10AMAPTTSHRRECQLNPSR1 | |
| SCHEMBL4772353 | 0.89 | PDE10A (0.32) | PDE10AMAPTTSHRRECQLNPSR1 | |
| SCHEMBL4776059 | 0.88 | PDE10A (0.33) | PDE10AMAPTTSHRRECQLNPSR1 | |
| SCHEMBL4772675 | 0.87 | SMN1; SMN2 (0.32) | PDE10AMAPTTSHRRECQLNPSR1 | |
| SCHEMBL4772687 | 0.87 | SMN1; SMN2 (0.32) | PDE10AMAPTTSHRRECQLNPSR1 | |
| SCHEMBL4776041 | 0.85 | SMN1; SMN2 (0.30) | MAPTTSHRNPSR1 | |
| SCHEMBL4776057 | 0.85 | SMN1; SMN2 (0.30) | MAPTTSHRNPSR1 | |
| SCHEMBL5117332 | 0.83 | MEN1 (0.33) | MAPTTSHRNPSR1 | |
| SCHEMBL5117322 | 0.83 | MEN1 (0.33) | MAPTTSHRNPSR1 | |
| SCHEMBL27682153 | 0.83 | PDE10A (0.36) | PDE10AMAPTTSHRRECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763528-B1 | PYRAZOLOPYRIDINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2008-11-26 | — | — | EP | disclosed |