Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776171 | 0.88 | TRPV1 (0.47) | CCNE1CDK2CDK5TRPV1CYP3A4 | |
| SCHEMBL4773992 | 0.85 | TRPV1 (0.45) | CCNE1CDK2CDK5TRPV1CYP3A4 | |
| SCHEMBL4777964 | 0.85 | TRPV1 (0.47) | CCNE1CDK2CDK5TRPV1CYP3A4 | |
| SCHEMBL4776314 | 0.82 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4780425 | 0.81 | TRPV1 (0.49) | CCNE1CDK2CDK5TRPV1CYP3A4 | |
| SCHEMBL4778063 | 0.79 | CHRM1 (0.48) | TRPV1 | |
| SCHEMBL4773951 | 0.79 | TRPV1 (0.56) | TRPV1CYP3A4 | |
| SCHEMBL4780302 | 0.78 | TRPV1 (0.52) | TRPV1CYP3A4 | |
| SCHEMBL4778224 | 0.78 | TRPV1 (0.53) | CCNE1CDK2CDK5TRPV1CYP3A4 | |
| SCHEMBL4773955 | 0.77 | TRPV1 (0.59) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |