Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528856 | 0.83 | AKR1B1 (0.43) | HTR6AKR1B1HTR2CHTR2BDRD2 | |
| SCHEMBL3532362 | 0.83 | HTR6 (0.43) | HTR6AKR1B1HTR2CHTR2B | |
| SCHEMBL4793058 | 0.81 | SLC22A12 (0.41) | HTR6AKR1B1HTR2CHTR2BDRD2 | |
| SCHEMBL8239690 | 0.78 | HTR6 (0.71) | HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3539148 | 0.77 | HTR6 (0.71) | HTR6HTR2CHTR2B | |
| SCHEMBL3533483 | 0.77 | HTR6 (0.52) | HTR6AKR1B1HTR2CHTR2B | |
| SCHEMBL4778335 | 0.77 | HTR6 (0.72) | HTR6HTR2CHTR2B | |
| SCHEMBL3533189 | 0.77 | HTR6 (0.48) | HTR6HTR2CHTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL3532758 | 0.76 | HTR6 (0.51) | HTR6AKR1B1HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3539756 | 0.76 | HTR6 (0.72) | HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931640-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth a Corporation of the State of Delaware (US) | 2008-06-18 | — | — | EP | claimed |
| WO-2007021711-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-02-22 | — | — | WO | claimed |