Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973246 | 0.92 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2RXFP1MTNR1A | |
| Trifluoroacetic Acid SCHEMBL4777180 | 0.84 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2RXFP1MTNR1A | |
| Trifluoroacetic Acid SCHEMBL4777187 | 0.78 | HCRTR1 (0.39) | NPC1RAB9ASMN1; SMN2EGFRHTT | |
| SCHEMBL5269323 | 0.75 | MTNR1A (0.47) | MTNR1AMTNR1BTGM2 | |
| Trifluoroacetic Acid SCHEMBL4778437 | 0.74 | CAPN1 (0.38) | NPC1RAB9ARXFP1L3MBTL1HTT | |
| SCHEMBL23532112 | 0.74 | NR1I3 (0.58) | NPC1RAB9ASMN1; SMN2RXFP1MTNR1A | |
| SCHEMBL4778585 | 0.74 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2RXFP1MTNR1A | |
| Hydrochloric Acid SCHEMBL30481157 | 0.73 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2RXFP1MTNR1A | |
| SCHEMBL23532074 | 0.72 | ABL1 (0.41) | RAB9ASMN1; SMN2GAAL3MBTL1BTK | |
| Trifluoroacetic Acid SCHEMBL27785538 | 0.68 | KCNH2 (0.49) | NPC1RAB9ASMN1; SMN2RXFP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | disclosed |