Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | STAT1 | P42224 | 1/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27452405 | 0.83 | STAT1 (0.69) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL16229848 | 0.83 | EGFR (0.66) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL7500128 | 0.82 | STAT1 (0.67) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL4725990 | 0.82 | MAPK1 (0.59) | MAPK1HTTSTAT1RAF1KDM4E | |
| Hydrochloric Acid SCHEMBL7502866 | 0.81 | STAT1 (0.66) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL4729789 | 0.78 | PDE11A (0.69) | MAPK1STAT1EGFR | |
| SCHEMBL4727894 | 0.78 | PDE11A (0.72) | — | |
| SCHEMBL4728689 | 0.78 | PDE5A (0.55) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL4727580 | 0.78 | PDE5A (0.55) | MAPK1HTTSTAT1RAF1KDM4E | |
| SCHEMBL643991 | 0.78 | EGFR (0.68) | MAPK1HTTSTAT1RAF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020711-A1 | QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-02-21 | — | — | WO | disclosed |