Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15508071 | 0.81 | — | — | |
| SCHEMBL2624132 | 0.81 | AURKA (0.39) | CYP3A4CYP2D6CYP2C9SCN9A | |
| SCHEMBL16369877 | 0.77 | ALDH1A1 (0.38) | DAO | |
| SCHEMBL28883214 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL14482528 | 0.75 | — | — | |
| SCHEMBL29444684 | 0.73 | ALDH1A1 (0.48) | SCN9A | |
| SCHEMBL15111181 | 0.73 | ALDH1A1 (0.44) | CYP3A4CYP2C9 | |
| SCHEMBL4965560 | 0.72 | IDO1 (0.36) | CYP3A4CYP2D6CYP2C9SCN9A | |
| SCHEMBL2745784 | 0.71 | HTR2B (0.49) | CYP3A4CYP2D6CYP2C9SCN9AHTR2B | |
| SCHEMBL164484 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004819-A | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119101010-A | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2024-12-10 | — | — | CN | claimed |
| EP-1987003-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093542-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | claimed |
| US-20070197553-A1 | 4-Aryl-pyridine-2-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. | 2007-08-23 | — | — | US | claimed |
| CN-120004819-B | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-11-14 | — | — | CN | disclosed |
| CN-120004819-B | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-11-14 | — | — | CN | disclosed |
| CN-120081788-A | Pyrazole amide compound containing 2- (4-bromo-2- (trifluoromethyl) phenoxy) phenyl fragment and application thereof | 安徽理工大学 | 2025-06-03 | — | — | CN | disclosed |
| CN-120004819-A | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-120004819-A | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-120004819-A | Difluoromethyl thiazole amide compound containing diphenyl ether and application thereof | 安徽理工大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119101010-A | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-119101010-A | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-119101010-A | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2024-12-10 | — | — | CN | disclosed |
| EP-1987003-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093542-A1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| US-20070197553-A1 | 4-Aryl-pyridine-2-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197553-A1 | 4-Aryl-pyridine-2-carboxyamide derivatives | GRM2, GRM1, GRM3 | CYP3A4 2111/4885CYP2D6 2466/4885CYP2C9 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.