SCHEMBL4778767

SCHEMBL4778767

CC1(C(=O)OCCO)CS1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ACHE P22303 1/20 0.32
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499775 0.83 HCAR2 (0.35) TSHRSMN1; SMN2KMT2A
SCHEMBL18415750 0.78 TSHR (0.33) TSHRSMN1; SMN2ACHE
SCHEMBL27699115 0.76 FFAR3 (0.40) TSHRSMN1; SMN2ACHEHSD17B10
SCHEMBL21253274 0.73
SCHEMBL9490606 0.71 SMN1; SMN2 (0.36) TSHRSMN1; SMN2ACHE
SCHEMBL19569912 0.67 SMN1; SMN2 (0.33) TSHRSMN1; SMN2ACHE
SCHEMBL16561549 0.66 TSHR (0.31) TSHR
SCHEMBL14431612 0.64 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL25433243 0.64 TSHR (0.35) TSHRKMT2AHSD17B10
SCHEMBL28971898 0.64 TSHR (0.35) TSHRKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1908788-A1 Novel biomimetic hydrogel materials The Regents of the University of California (US) 2008-04-09 EP claimed
EP-1017737-B1 NOVEL BIOMIMETIC HYDROGEL MATERIALS UNIV CALIFORNIA (US) 2008-01-23 EP claimed
EP-1017737-A4 NOVEL BIOMIMETIC HYDROGEL MATERIALS UNIV CALIFORNIA (US) 2002-06-26 EP claimed
EP-1017737-A1 NOVEL BIOMIMETIC HYDROGEL MATERIALS The Regents of the University of California (US) 2000-07-12 EP claimed
WO-1999011692-A1 NOVEL BIOMIMETIC HYDROGEL MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-03-11 WO claimed