SCHEMBL25433243

SCHEMBL25433243

O=C(OCCO)C1(C(=O)OCCO)CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
SIGMAR1 Q99720 5/20 0.35
CYP3A4 P08684 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
CHRM2 P08172 2/20 0.35
CHRM1 P11229 2/20 0.35
ABCB11 O95342 1/20 0.35
LMNA P02545 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
DRD1 P21728 1/20 0.35
HRH2 P25021 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SCN1A P35498 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28971898 1.00 TSHR (0.35) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL2703469 0.90 CYP2C19 (0.35) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL28434616 0.86 CYP4F2 (0.42) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL11166080 0.81 CYP3A4 (0.34) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL234284 0.81 CYP3A4 (0.41) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL9987436 0.80 CHRM2 (0.39) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL16086270 0.78 TSHR (0.38) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL234860 0.78 ALDH1A1 (0.47) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL11303514 0.76 CYP4F2 (0.41) TSHRSIGMAR1CYP3A4CYP1A2CYP2D6
SCHEMBL16086086 0.76 NAAA (0.46) TSHRCYP3A4LMNAMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023173791-A1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF 中国科学院宁波材料技术与工程研究所 2023-09-21 WO disclosed
CN-114591606-B Fast crystallization polyester composite material, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-02-17 CN disclosed
CN-114591606-A Fast crystallization polyester composite material, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-06-07 CN disclosed
CN-107417526-B Process for preparing 1,4-cyclohexane dicarboxylic acid dihydroxy ethyl ester and its derivative 远东新世纪股份有限公司 2020-09-25 CN disclosed
CN-1228385-C Flameproofed thermoplastic molding compounds BASF AG (DE) 2005-11-23 CN disclosed