Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.36 |
| ▸ | MELK | Q14680 | 5/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375899 | 0.79 | MTNR1B (0.52) | MTNR1BMTNR1ASSTR2MELKAXL | |
| SCHEMBL3375900 | 0.79 | MTNR1B (0.52) | MTNR1BMTNR1ASSTR2MELKAXL | |
| SCHEMBL4773074 | 0.79 | MTNR1B (0.39) | MTNR1BMTNR1A | |
| SCHEMBL3779200 | 0.77 | SLC2A1 (0.47) | MTNR1BMTNR1ASSTR2 | |
| SCHEMBL3780018 | 0.76 | MTNR1B (0.48) | MTNR1BMTNR1APDE4B | |
| SCHEMBL5503277 | 0.74 | MTNR1B (0.41) | MTNR1BMTNR1ASSTR2 | |
| SCHEMBL5264168 | 0.73 | MTNR1B (0.41) | MTNR1BMTNR1A | |
| SCHEMBL21783731 | 0.71 | MTNR1B (0.47) | MTNR1BMTNR1APDE4B | |
| SCHEMBL4773064 | 0.70 | MTNR1B (0.39) | MTNR1BMTNR1A | |
| SCHEMBL3776044 | 0.68 | SLC2A1 (0.41) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093963-A1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-23 | — | — | WO | disclosed |