Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776343 | 0.90 | MEN1 (0.45) | KMT2AMEN1HTR6ALDH1A1ACLY | |
| SCHEMBL4794414 | 0.87 | HTR6 (0.40) | KMT2AMEN1HTR6LMNAHTT | |
| SCHEMBL948940 | 0.85 | HTT (0.44) | HTR6LMNAHTTTSHRBRD4 | |
| SCHEMBL4779065 | 0.85 | PPARG (0.49) | HTR6SMN1; SMN2MAPT | |
| SCHEMBL4778308 | 0.83 | HTR6 (0.42) | KMT2AMEN1HTR6ALDH1A1LMNA | |
| SCHEMBL4777851 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1ACLYLMNA | |
| SCHEMBL4772180 | 0.78 | HTR6 (0.40) | KMT2AMEN1HTR6LMNAHTT | |
| SCHEMBL947170 | 0.77 | HTT (0.44) | KMT2AMEN1HTR6ALDH1A1LMNA | |
| SCHEMBL949419 | 0.77 | HTR6 (0.54) | HTR6 | |
| SCHEMBL4772761 | 0.77 | HTR6 (0.47) | HTR6SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |