Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.64 |
| ▸ | XDH | P47989 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525493 | 0.83 | MAPT (0.75) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13279932 | 0.83 | MAPT (0.75) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18676275 | 0.81 | MAPT (0.68) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14350888 | 0.80 | MAPT (0.55) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18326518 | 0.80 | EGFR (0.70) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18312072 | 0.80 | ALOX15 (0.57) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16431178 | 0.80 | EGFR (0.67) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14506910 | 0.79 | EGFR (0.65) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| Genistein SCHEMBL554056 | 0.78 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| Genistein SCHEMBL29352944 | 0.78 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218489-A | Antioxidants, antioxidant compositions and methods of preparing and using same | Z-L LIMITED PARTNERSHIP (US) | 1980-08-19 | — | — | US | claimed |
| US-4157984-A | Antioxidants, antioxidant compositions and methods of preparing and using same | Z-L Limited (US) | 1979-06-12 | — | — | US | claimed |
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-4232122-A | Antioxidants, antioxidant compositions and methods of preparing and using same | Z-L LIMITED PARTNERSHIP (US) | 1980-11-04 | — | — | US | disclosed |
| US-4218489-A | Antioxidants, antioxidant compositions and methods of preparing and using same | Z-L LIMITED PARTNERSHIP (US) | 1980-08-19 | — | — | US | disclosed |
| US-4157984-A | Antioxidants, antioxidant compositions and methods of preparing and using same | Z-L Limited (US) | 1979-06-12 | — | — | US | disclosed |