Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022338 | 0.94 | MEN1 (0.32) | MC4RMEN1KMT2A | |
| SCHEMBL4019857 | 0.93 | MC4R (0.31) | MC4RMEN1KMT2A | |
| SCHEMBL4021534 | 0.92 | MEN1 (0.34) | MC4RMEN1KMT2A | |
| SCHEMBL4020633 | 0.87 | MEN1 (0.35) | MC4RMEN1KMT2A | |
| SCHEMBL4022527 | 0.85 | CARM1 (0.31) | MEN1KMT2A | |
| SCHEMBL4023509 | 0.85 | CARM1 (0.31) | MEN1KMT2A | |
| SCHEMBL4025180 | 0.84 | MEN1 (0.35) | MC4RMEN1KMT2A | |
| SCHEMBL4751303 | 0.83 | KDM2B (0.33) | MC4RMEN1KMT2A | |
| SCHEMBL4022172 | 0.83 | CARM1 (0.32) | MEN1KMT2A | |
| SCHEMBL4019668 | 0.83 | HRH2 (0.34) | MC4RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |