Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020633 | 0.96 | MEN1 (0.35) | KDM2BMEN1KMT2AESRRGMGLL | |
| SCHEMBL4028155 | 0.91 | KMT2A (0.34) | KDM2BMEN1KMT2AESRRGMGLL | |
| SCHEMBL4019668 | 0.90 | HRH2 (0.34) | KDM2BMEN1KMT2AESRRGMGLL | |
| SCHEMBL4779145 | 0.90 | MC4R (0.40) | KDM2BNTRK1MC4RKDM4E | |
| SCHEMBL4779138 | 0.90 | MC4R (0.40) | KDM2BNTRK1MC4RKDM4E | |
| SCHEMBL4025770 | 0.89 | KDM2B (0.41) | KDM2BMEN1KMT2AMGLLALDH1A1 | |
| SCHEMBL4024566 | 0.88 | EED (0.33) | KDM2BMEN1KMT2A | |
| SCHEMBL4020144 | 0.88 | DPP4 (0.38) | KDM2BMGLLMC4RKDM4EALDH1A1 | |
| SCHEMBL4022073 | 0.88 | MEN1 (0.36) | KDM2BMEN1KMT2AMGLLMC4R | |
| SCHEMBL4029269 | 0.88 | KDM2B (0.35) | KDM2BMEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |