Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312395 | 0.84 | PDE4D (1.00) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL31166478 | 0.84 | PDE4D (1.00) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL22782398 | 0.79 | PDE4D (0.73) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL3262735 | 0.79 | PDE4D (0.83) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL21255976 | 0.75 | PDE4D (1.00) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL11741335 | 0.75 | PDE4D (0.80) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL26654641 | 0.75 | PDE4D (0.80) | PDE4DMAOBMAOASLC6A4CA7 | |
| SCHEMBL7702933 | 0.74 | MAOA (0.47) | MAOBMAOATHRBMAPTTSHR | |
| SCHEMBL7697759 | 0.73 | AKR1C3 (0.38) | PDE4DGAAKMT2ANPC1MEN1 | |
| SCHEMBL21255798 | 0.72 | PDE4D (0.74) | PDE4DMAOBMAOASLC6A4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |