Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779334 | 0.83 | — | — | |
| SCHEMBL4779060 | 0.74 | CYP1A2 (0.42) | — | |
| SCHEMBL4778154 | 0.65 | ABL1 (0.34) | — | |
| SCHEMBL4779481 | 0.65 | DPP8 (0.54) | DPP8DPP9NAMPT | |
| SCHEMBL4794727 | 0.65 | DPP8 (0.54) | DPP8DPP9NAMPT | |
| SCHEMBL9963375 | 0.64 | DPP8 (0.46) | DPP8DPP9NAMPTADORA2A | |
| SCHEMBL19104710 | 0.63 | ADORA2A (0.39) | DPP8DPP9NAMPTADORA2A | |
| SCHEMBL8189202 | 0.61 | TIPARP (0.40) | DPP8DPP9NAMPT | |
| SCHEMBL20651754 | 0.60 | DPP8 (0.51) | DPP8DPP9NAMPTADORA2A | |
| SCHEMBL19116855 | 0.59 | DPP8 (0.44) | DPP8DPP9NAMPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996550-A2 | CARBOXYAMINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF HDAC DEPENDENT DISEASES | Novartis AG (CH) | 2008-12-03 | — | — | EP | claimed |
| WO-2007038459-A2 | CARBOXYAMINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF HDAC DEPENDENT DISEASES | NOVARTIS AG (CH) | 2007-04-05 | — | — | WO | claimed |