SCHEMBL4779633

SCHEMBL4779633

Cc1nsc(-n2ncc(C#N)c2N=NC(C(=O)Nc2ccccc2O)c2nc3ccccc3c(=O)[nH]2)n1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.33
PARP1 P09874 1/20 0.32
PARP2 Q9UGN5 1/20 0.32
G6PD P11413 1/20 0.32
MEN1 O00255 2/20 0.31
PDE5A O76074 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SPR P35270 1/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30
MALT1 Q9UDY8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742736 0.91 PDE9A (0.39) PARP2NPC1SPR
SCHEMBL12946223 0.89 PDE5A (0.33) KMT2APARP1PARP2G6PDMEN1
SCHEMBL4779611 0.88 KMT2A (0.34) KMT2APARP1PARP2G6PDMEN1
SCHEMBL4779635 0.88 RAB9A (0.43) KMT2APARP1PARP2G6PDPDE5A
SCHEMBL10280956 0.86 PARP1 (0.34) KMT2APARP1PARP2G6PDMEN1
SCHEMBL4767781 0.85 NPC1 (0.31) PDE5ANPC1RAB9A
SCHEMBL4779605 0.84 PARP1 (0.35) KMT2APARP1PARP2G6PDMEN1
SCHEMBL4779657 0.84 PDE5A (0.34) KMT2APARP1PARP2G6PDMEN1
SCHEMBL4779662 0.84 MALT1 (0.33) KMT2APARP1PARP2PDE5AMALT1
SCHEMBL4779639 0.83 PARP1 (0.34) KMT2APARP1PARP2G6PDPDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed