Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 9/20 | 0.46 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367570 | 0.88 | L3MBTL1 (0.46) | L3MBTL1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL4353089 | 0.85 | CNR1 (0.43) | L3MBTL1CNR1CNR2LMNATSHR | |
| SCHEMBL4358480 | 0.81 | L3MBTL1 (0.45) | L3MBTL1CNR1LMNAKDM4EHSD17B10 | |
| SCHEMBL4366103 | 0.78 | CNR1 (0.46) | L3MBTL1CNR1CNR2LMNAKDM4E | |
| SCHEMBL4355355 | 0.76 | GBA1 (0.47) | L3MBTL1LMNAMEN1KMT2ATSHR | |
| SCHEMBL4351924 | 0.74 | RAF1 (0.56) | L3MBTL1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4355357 | 0.74 | GBA1 (0.45) | L3MBTL1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL5335588 | 0.67 | L3MBTL1 (0.91) | L3MBTL1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL4095539 | 0.67 | KMT2A (0.47) | L3MBTL1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL4737806 | 0.67 | EGFR (0.54) | KDM4EMEN1KMT2AHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009078-A2 | 4,6-DL- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |