⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23829501 | 0.79 | HTT (0.31) | — | |
| SCHEMBL4578975 | 0.77 | LMNA (0.40) | — | |
| SCHEMBL178478 | 0.77 | — | — | |
| SCHEMBL25238270 | 0.74 | — | — | |
| SCHEMBL5961020 | 0.74 | — | — | |
| SCHEMBL27476120 | 0.74 | HTT (0.34) | — | |
| SCHEMBL16591016 | 0.74 | HTT (0.34) | — | |
| SCHEMBL1148780 | 0.74 | — | — | |
| SCHEMBL27476121 | 0.74 | HTT (0.34) | — | |
| SCHEMBL14438874 | 0.72 | HTT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015196-A1 | 5-,7-BIS-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES | NYCOMED GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |
| US-20070244154-A1 | Substituted Tricyclic Benzimidazoles | ALTANA PHARMA AG (DE) | 2007-10-18 | — | — | US | disclosed |
| EP-1758900-B1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2007-10-03 | — | — | EP | disclosed |
| EP-1824850-A2 | SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION | Nycomed GmbH (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-1758900-A1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | Altana Pharma AG (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006061380-A2 | SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION | ALTANA PHARMA AG (DE) | 2006-06-15 | — | — | WO | disclosed |
| WO-2005121139-A1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2005-12-22 | — | — | WO | disclosed |