Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732315 | 0.88 | MAPK1 (0.50) | EBPDHCR7FABP6MAPK1ACHE | |
| SCHEMBL5086408 | 0.83 | CHRM1 (0.50) | MAPK1CHRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4725455 | 0.80 | ROCK2 (0.60) | EBPDHCR7FABP6MAPK1OPRK1 | |
| SCHEMBL7318271 | 0.79 | CHRM1 (0.55) | MAPK1CHRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4727809 | 0.79 | CHRM1 (0.51) | CHRM1SMN1; SMN2HTR1ADRD2HTR2A | |
| SCHEMBL4727540 | 0.77 | FABP6 (0.47) | FABP6MAPK1OPRM1OPRK1SMN1; SMN2 | |
| SCHEMBL7312944 | 0.75 | CHRM1 (0.53) | MAPK1CHRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7352432 | 0.75 | CHRM1 (0.56) | MAPK1CHRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4730348 | 0.75 | CHRM1 (0.53) | MAPK1CHRM1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4726186 | 0.75 | CHRM1 (0.47) | MAPK1CHRM1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021210-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | CHDI, INCORPORATED | 2008-02-21 | — | — | US | disclosed |
| US-4798897-A | (AMINOALKYL)AMINOSULFONYL-SUBSTITUTED CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | HTT, SNCA, NLN | EBP 799/4885DHCR7 1557/4885FABP6 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.