Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725020 | 0.94 | MAPT (0.44) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4584112 | 0.93 | MAPT (0.44) | ALDH1A1MAPTKMT2ARAB9AMAPK1 | |
| SCHEMBL4584003 | 0.93 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4582143 | 0.90 | NPC1 (0.45) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4583673 | 0.87 | EGFR (0.48) | RAB9ASMN1; SMN2 | |
| SCHEMBL4583028 | 0.86 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4582547 | 0.86 | MAPT (0.44) | ALDH1A1MAPTKMT2ARAB9AMAPK1 | |
| SCHEMBL4727782 | 0.85 | RAB9A (0.43) | ALDH1A1MAPTKMT2ARAB9AMAPK1 | |
| SCHEMBL4726353 | 0.85 | NPC1 (0.40) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4583648 | 0.84 | MAPK14 (0.46) | ALDH1A1MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |