Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582075 | 0.98 | MALT1 (0.45) | MALT1HRH4SIGMAR1MAPTRXFP1 | |
| SCHEMBL4582822 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MAPK1KMT2AHRH4 | |
| SCHEMBL4584337 | 0.90 | MALT1 (0.45) | MALT1KMT2AHRH4 | |
| SCHEMBL4582726 | 0.87 | POLB (0.53) | MALT1ALDH1A1HRH4POLB | |
| SCHEMBL4583157 | 0.85 | MALT1 (0.51) | MALT1ALDH1A1MAPK1MAPT | |
| SCHEMBL4584127 | 0.83 | HTT (0.56) | MALT1ALDH1A1KMT2AHRH4 | |
| SCHEMBL4583253 | 0.83 | HTR2C (0.45) | MALT1HRH4 | |
| SCHEMBL4583335 | 0.82 | MEN1 (0.55) | MALT1ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL4725222 | 0.82 | HTT (0.46) | MALT1ALDH1A1KMT2AHRH4 | |
| SCHEMBL4581567 | 0.81 | MALT1 (0.45) | MALT1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |