Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781009 | 1.00 | SCD (0.52) | SCDLMNAKDM4ESMN1; SMN2GRM5 | |
| SCHEMBL4728133 | 0.91 | SCD (0.53) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL4778897 | 0.91 | SCD (0.53) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL14261415 | 0.90 | SCD (0.53) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL14261331 | 0.88 | SCD (0.52) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL4783924 | 0.85 | SCD (0.51) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL14261408 | 0.85 | SCD (0.51) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL14261407 | 0.85 | SCD (0.50) | SCDLMNAKDM4ESMN1; SMN2HTT | |
| SCHEMBL14261330 | 0.82 | SCD (0.54) | SCD | |
| SCHEMBL14261405 | 0.80 | ALDH1A1 (0.54) | LMNAKDM4ESMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | claimed |
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | disclosed |