Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111131 | 0.80 | IDO1 (0.58) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL11219362 | 0.78 | PNMT (0.64) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL7328450 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL184185 | 0.76 | TAAR1 (1.00) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL177296 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL16404687 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL3565937 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL8494705 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL2991065 | 0.76 | PNMT (0.61) | PNMTTAAR1IDO1SIGMAR1IGF1R | |
| SCHEMBL6011638 | 0.76 | IDO1 (0.67) | PNMTTAAR1IDO1SIGMAR1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |