Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PNLIP | P16233 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaminosalol SCHEMBL30383652 | 0.98 | HPGD (1.00) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL25220 | 0.98 | HPGD (1.00) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL8667882 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL579853 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL4777453 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL579851 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL18149032 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL2521697 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL27692402 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL3041383 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2008090081-A1 | METAL SALOPHEN COMPLEXES FOR PREVENTION AND TREATMENT OF CANCER | FREIE UNIVERSITÄT BERLIN (DE) | 2008-07-31 | — | — | WO | disclosed |
| EP-1949899-A1 | Metal salophen complexes use in prevention and treatment of cancer | Freie Universität Berlin (DE) | 2008-07-30 | — | — | EP | disclosed |
| EP-1949899-A1 | Metal salophen complexes use in prevention and treatment of cancer | Freie Universität Berlin (DE) | 2008-07-30 | — | — | EP | disclosed |