Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PNLIP | P16233 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaminosalol SCHEMBL30383652 | 0.98 | HPGD (1.00) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL25220 | 0.98 | HPGD (1.00) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL8667882 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL579853 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL4777453 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL579851 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL18149032 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL4780360 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL27692402 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA | |
| Acetaminosalol SCHEMBL3041383 | 0.97 | HPGD (0.97) | HPGDHSD17B10ALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190012-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-06-18 | — | — | US | claimed |
| US-10196341-B2 | C-halogen bond formation | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-02-05 | — | — | US | claimed |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | claimed |
| EP-2744771-B1 | C-HALOGEN BOND FORMATION | UNIV PRINCETON (US) | 2020-10-21 | — | — | EP | disclosed |
| US-20200190012-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-06-18 | — | — | US | disclosed |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-02 | — | — | US | disclosed |
| US-10196341-B2 | C-halogen bond formation | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-02-05 | — | — | US | disclosed |
| EP-2384325-B1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | BLUE CUBE IP LLC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-09-15 | — | — | US | disclosed |
| CN-104529946-A | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES LLC | 2015-04-22 | — | — | CN | disclosed |
| WO-2015054476-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | disclosed |
| EP-2744771-A1 | C-HALOGEN BOND FORMATION | The Trustees of Princeton University (US) | 2014-06-25 | — | — | EP | disclosed |
| US-8497387-B2 | Process for preparing divinylarene dioxides | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-30 | — | — | US | disclosed |
| WO-2013081685-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-06-06 | — | — | WO | disclosed |
| WO-2013028639-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-02-28 | — | — | WO | disclosed |
| CN-102272113-A | Process for preparing divinylarene dioxides | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2384325-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | Dow Global Technologies LLC (US) | 2011-11-09 | — | — | EP | disclosed |
| US-20110251412-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | BLUE CUBE IP LLC | 2011-10-13 | — | — | US | disclosed |
| WO-2010077483-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190012-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | HPGD 3589/4885HSD17B10 1746/4885ALDH1A1 3157/4885 |
| US-20110251412-A1 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES | HAO2, DBN1, PPOX | HPGD 90/4885HSD17B10 202/4885ALDH1A1 2572/4885 |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | HPGD 3589/4885HSD17B10 1746/4885ALDH1A1 3157/4885 |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | FOS, BCL3, CBR3 | HPGD 4306/4885HSD17B10 2491/4885ALDH1A1 3937/4885 |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | HPGD 3589/4885HSD17B10 1746/4885ALDH1A1 3157/4885 |
| US-10196341-B2 | C-halogen bond formation | CBR3, FOS, CBR1 | HPGD 3589/4885HSD17B10 1746/4885ALDH1A1 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.